基本信息:
性别:男
学历:博士研究生
职称:副教授
邮箱:zhang19870711@163.com
教育背景:
2005.09 – 2009.06 中国海洋大学 生物科学专业 学士
2009.09– 2014.06 中国海洋大学 细胞生物学专业 博士
工作经历:
2014.08–至今 济宁医学院生命科学学院生物技术教研室
教授课程:
基因工程、生物药物分析和网络药理学等。
研究领域及方向:
主要从事中药活性提取物对人类疾病例如非酒精性脂肪肝、糖尿病以及癌症的作用分析机制研究以及海洋活性物质的研究。
发表文章:
1. Zhang Litao, Wang S, Li Y, Liu B, Duan Z, Liu F, Ren Q. Tartary buckwheat root polysaccharides ameliorate non-alcoholic fatty liver disease via the IL6-SOCS3-SREBP1c pathway. Food Chem Toxicol. 2023 Sep;179:113997. doi: 10.1016/j.fct.2023.113997. Epub 2023 Aug 19. PMID: 37604299.
2. Ren Qiang; Sun Shanshan; Li Meiyi; Gao Bo; Zhang Litao*(通讯作者); Structural characterization and tartary buckwheat polysaccharides alleviate insulin resistance by suppressing SOCS3-induced IRS1 protein degradation, Journal of Functional Foods, 2022, 89: 104961
3. Zhang Litao; Liu Chao; Gao Huijie; Zhou Caiju; Qin Wei; Wang Jian; Meng Lingxin; Wang Huiyun; Ren Qiang; Zhang Yuntao ; Study on the expression profile and role of decorin in the progression of pancreatic cancer., Aging, 2021, 13(11): 14989-14998
4. Ren, Qiang; Wang, Jian; Liu, Chao; Meng, Lingxin; Qian, Ruikun; Gao, Huijie; Qin, Wei; Zhou, Caiju; Qiao, Sen; Wang, Huiyun; Zhang, Litao*(通讯作者); Zhang, Yuntao*; Exploring the sulfate patterns of chondroitin sulfate/dermatan sulfate and keratan sulfate in human pancreatic cancer, Journal of Pharmaceutical and Biomedical Analysis, 2021, 205: 114339
5. Zhang, Litao; Cui, Wei; Chen, Qian; Ren, Qiang; Zhu, Youshuang; Zhang, Yuran*; Thymosin-β12 characteristics and function in Urechis unicinctus., Comparative Biochemistry and Physiology B-Biochemistry & Molecular Biology, 2020, 239: 110366.
6. Zhang Litao; Xiaolong Liu; Zhenkui Qin; Jianguo Liu; Zhifeng Zhang*; Expression characteristics of sulfur dioxygenase and its function adaption to sulfide in echiuran worm Urechis unicinctus, Gene, 2016, 593(2): 334-341.
7. Gao, Bo; Ma, Yu; Zhang, Litao*(通讯作者); Ren, Qiang*; Identification and characterization of the chemical components of Iris tectorum Maxim. and evaluation of their nitric oxide inhibitory activity., Rapid Communications in Mass Spectrometry, 2021, 35(1): e8959
8. Zhang Litao*; Zhang Zhifeng*; The response of sulfur dioxygenase to sulfide in the body wall of Urechis unincinctus., PeerJ, 2019, 7: e6544.
9. 张立涛*; 崔巍; 陈茜; 毕愿坤; 单环刺螠泛素基因的克隆及表达, 济宁医学院学报, 2018, (06): 396-399.